Abstrato

The role of the skin biopsy in the diagnosis of atypical dermatoses of pregnancy.

Eman Talat Eleskafy*, Mohamed Khalafallla, El Sayed Elshamy

Objectives: The aim of the study is to evaluate the benefits of skin biopsy in pregnant women complained of skin lesions during pregnancy.
Patients and methods: Women with pregnancy induced skin lesions were included in this prospective study, evaluated clinically by history and examination. Skin biopsy was performed between 28 and 39 weeks of pregnancy. Patients were classified according to the clinical diagnosis into two groups: typical and atypical dermatosis.
Results: One hundred ninety eight women with skin lesions during pregnancy were included. All patients underwent skin biopsy, 3 patients excluded from the study due to their abnormal coagulation profiles Based on skin biopsy results, The diagnosis of intrahepatic cholestasis was noted in 33 patients were diagnosed as eruption of pregnancy, 9 patients as pruritic folliculitis and 3 as pemphigoid gestations.
Conclusions: Routine skin biopsy should be used as a basic part of the work-up for women with atypical dermatoses of pregnancy.