Jornal de Gastroenterologia e Doenças Digestivas

Abstrato

The effects of exogenous ketones on biomarkers of Crohn’s disease: A case report.

Ryan P. Lowery*, Jacob M. Wilson, Matthew H. Sharp, Gabriel J. Wilson, Ronald Wagner

In this paper, we report on a case study in which exogenous ketone supplementation lowered markers of CRP significantly and improved quality of life in an individual suffering from Crohn’s disease. As a result, this study is significant because Crohn’s disease is a growing autoimmune disease that is characterized by chronic inflammation. Moreover, this study is the first of its kind showing that betahydroxbutyrate (BHB) might combat some of that inflammation due to its anti-inflammatory properties that have been previously studied. Accordingly, this research could accelerate insight and investigation into the use of exogenous ketones and specifically BHB for digestive diseases that are characterized by excessive, chronic inflammation.