Abstrato

Plasmablastic lymphoma presenting as a large cervical-thoracic mass: Report of a case and literature review.

Marcelo Corti, Luis De Carolis, Jorge Correa, Ana Campitelli, Marina Narbaitz

Plasmablastic lymphoma (PBL) was first described in the jaws and the oral cavity of human immunodeficiency virus infected patients. This subtype of lymphoma is considered as a variant of the diffuse large B-cell lymphoma with a phenotype of plasma cell differentiation that expresses markers such as CD38, CD138 and MUM1 protein. HIV- associated PBL is associated with an aggressive clinical course, poor prognosis and shot survival even in the era of highly active antiretroviral therapy (HAART). Primary soft tissue Non-Hodgkin lymphomas (NHL) are very rare and account only the 0.1% of the cases. Generally, NHL of the soft tissue present as large subcutaneous masses, with fast growing and without evidence of nodal or skin involvement. Here we describe a primary NHL of the soft tissue in an HIV infected patient.