Abstrato

Gastric carcinoma recurring as an isolated breast secondary after three years from curative treatment.

Donnell SO, Abd Elwahab S, Auchwraz N, Lal A, Tormey S, Coate L, El-Bassiouni M

Extra-mammary tumour metastases to the breast are extremely rare accounting for less than 2% of all breast lesions. Breast secondaries were reported with lymphoma, melanoma, ovarian carcinoma, renal cell carcinoma, colonic adenocarcinoma and gastric carcinoma. Stomach cancer metastases to the breast are very rare, with an incidence believed to be around 2.1% of all breast secondaries. The presentation is usually quite similar to breast primary; therefore clinicians need to keep an open mind when discussing histology as additional immune-histo-pathological tests are usually necessary to fully diagnose the cancer. Our case was a 55-years-old female who was treated for gastric signet ring carcinoma in 2013. She was referred to our breast clinic three years post curative surgical and chemotherapeutic management of her stomach cancer with a right breast lump with oedema and thickening of the overlying skin. She was thought to have inflammatory breast carcinoma; however, further histological tests demonstrated signet ring cells consistent with metastatic gastric carcinoma. Radiological staging tests confirmed single isolated breast secondary with no other metastatic lesions. To best of our knowledge, this is the only case of isolated breast secondary from gastric tumour. In this report, we reviewed the literature; discussed patient presentation and management, including breast metastectectomy. Keywords: Gastric carcinoma,