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Formation of kidney stone and mechanisms of stone formation

Jiao Wang

Kidney stones form when your urine contains more crystal-forming substances such as calcium, oxalate and uric acid than the fluid in your urine can dilute. At the same time, your urine may lack substances that prevent crystals from sticking together, creating an ideal environment for kidney stones to form. Kidney stones can be caused by a variety of factors, including diet, excess body weight, various medical conditions, specific supplements, and drugs. Any component of your urinary tract, including your kidneys and bladder, might develop kidney stones. When urine becomes concentrated, minerals can crystallise and adhere to one another and frequently lead to stones.