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Episodic syncope and bradycardia due to small cell lung cancer: A case report.

Lianfang Ni, Hongmei Jiao, Zhifang Fu, Qingping Tian, Xianshu Gao

A 58-year-old woman with limited-disease small cell lung cancer (SCLC) presented with episodic syncope and bradycardia. Probable etiologies such as orthostatic hypotension, cardiac syncope, brain-derived syncope, and metabolic problems were excluded after extended examination. No further syncopal attacks were observed after the third day of the first course of chemotherapy. We finally diagnosed this case as neurally mediated syncope. Treatment of the underlying disease with chemotherapy or radiotherapy should be the main therapy for malignancy-related syncope.