Abstrato

Coagulation cascade and therapeutic interventions of Diabetic Macular Degeneration

Louis Zemanoili

Diabetic macular oedema is a leading cause of vision loss. Macular oedema aetiology appears to be multifaceted. The gold standard of therapy for macular oedema is laser photocoagulation. However, there are some circumstances where laser therapy is ineffective. For the therapy of this illness, several therapeutic strategies have been presented. Several variables and mechanisms implicated in the aetiology of macular oedema are discussed in this article (vasoactive factors, biochemical pathways, anatomical abnormalities). Combining pharmaceutical and surgical therapy appears to be the best technique for managing diabetic macular oedema