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A summary of research on molecular mechanism of action of traditional Chinese medicine for aiding neoadjuvant chemotherapy for breast cancer

Tang Binbin, Jiang Ying, Yang Hongjian, Zhang Xiping

Although neoadjuvant chemotherapy is a standard therapy for treating locally advanced breast cancer, it usually can’t achieve expected results owing to patients’ different chemotherapeutic sensitivity. At present, some certain progress have made in treating breast cancer by adjuvant chemotherapy combined with Traditional Chinese Medicine (TCM). Being effective for suppressing tumor growth, improving immunity, enhancing efficacy and removing toxicity, TCM can improve chemotherapy effects and patients’ prognosis. In this paper, the moderating roles of TCM in neoadjuvant chemotherapy for breast cancer are discussed from the perspective of molecular biology.